López-Medina, María DoloresLinares-Abad, ManuelLópez-Araque, Ana BelénLópez-Medina, Isabel M2024-05-022024-05-02201914. López-Medina M.D., Linares-Abad, M., López-Araque, A.B., López-Medina, I.M. Dry care versus chlorhexidine cord care for prevention of omphalitis. Systematic review with meta-analysis. Revista Latino-Americana de Enfermagem. 2019; V27: e3106. http://dx.doi.org/10.1590/1518-8345.2695.310610.1590/1518-8345.2695.3106https://hdl.handle.net/10953/2732Objective: to compare the effect of dry care and the application of chlorhexidine to the umbilical cord of newborns at risk of developing omphalitis. Method: systematic review with meta-analysis. Clinical trials comparing dry care with the application of clorexidine to evaluate omphalitis were selected. Methodological quality was evaluated using the Consolidated Standards of Reporting Trials. Results: the joint analysis of the studies shows a significant decrease in the risk of omphalitis in the chlorhexidine group compared to the dry care group (RR=0.58, CI: 0.53-0.64). However, in the analysis by subgroups, chlorhexidine umbilical cord care did not reduce the risk of omphalitis in hospital births (RR=0.82, CI: 0.64-1.05), in countries with a low infant mortality rate (RR=0.8, CI: 0.5-1.28), or at chlorhexidine concentrations below 4% (RR=0.55, CI: 0.31-1). Chlorhexidine acted as a protective factor at a concentration of 4% (RR=0.58, CI: 0.53-0.64), when applied in cases of home births (RR=0.57, CI: 0.51-0.62), in countries with a high infant mortality rate (RR=0.57, CI: 0.52-0.63). Conclusion: dry cord care is effective in countries with low infant mortality rate and in hospital births. However, 4% chlorhexidine for umbilical cord care protects against omphalitis in home births, in countries with a high infant mortality rate.engAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/Umbilical Cord; Chlorhexidine; Skin Care; Infection; Meta-Analysis; Infant, Newborninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccess