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dc.contributor.authorCastejón, Elena-
dc.contributor.authorFuentes-Verdugo, Esmeralda-
dc.contributor.authorPellón, Ricardo-
dc.contributor.authorTorres, Carmen-
dc.identifier.citationCastejón, E., Fuentes-Verdugo, E., Pellón, R., Torres, C. (2022). Physical activity reduces alcohol consumption induced by reward downshift.es_ES
dc.description.abstractIncreased voluntary consumption of alcohol and other anxiolytics has been demonstrated in animals after experiencing frustrative reward devaluation (downshift) or omission. These results have been interpreted in terms of emotional self-medication. In the present study we analyzed whether voluntary physical activity reduces alcohol intake induced by reward downshift. Sixty-four male Wistar rats were divided into eight groups (n=8). Thirty-two (downshifted) animals received 32% sucrose during 10 preshift sessions (5 min), followed by 4% sucrose during 5 postshift sessions, whereas 32 (unshifted) controls were always exposed to 4% sucrose. Immediately after each consummatory session, animals were exposed to a 2-h two-bottle preference test involving 32% alcohol vs. water, or water vs. water. Half of the animals had also access to a wheel for voluntary running during the preference test. The results showed lower sucrose consumption in downshifted groups compared with unshifted controls (the frustrative reward downshift effect). Reward downshift significantly increased alcohol intake, this effect being absent in downshifted animals with access to the wheel. These findings suggest that physical exercise could be useful to prevent alcohol self-medication induced by frustrative nonreward.es_ES
dc.description.sponsorshipPSI2017-87340-P, 2021V/PREMIO/04.es_ES
dc.publisherAmerican Psychological Associationes_ES
dc.relation.ispartofExperimental and Clinical Psychopharmacologyes_ES
dc.rightsCC0 1.0 Universal*
dc.subjectalcohol consumptiones_ES
dc.subjectemotional self-medicationes_ES
dc.subjectphysical activityes_ES
dc.subjectreward downshiftes_ES
dc.titlePhysical activity reduces alcohol consumption induced by reward downshiftes_ES
dc.subject.udc1 Filosofía. Psicologíaes_ES
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